Posts by: Alice Melao

Liver cancer, News

Radiation-delivering microspheres developed by Sirtex are as effective as Nexavar (sorafenib) chemotherapy against a liver cancer known as hepatocellular carcinoma (HCC), according to a Phase 3 clinical trial. Sirtex’s SIR-Spheres Y-90 ... Read more

April 24, 2017May 12, 2017

Enanta’s EDP-305 Therapy Shows Promise in Treating Non-Alcoholic Fatty Liver Disease

News, Non-alcoholic fatty liver disease

Candidate drug EDP-305 reduced fibrosis progression and improved non-alcoholic fatty liver disease (NAFLD) and primary biliary cholangitis (PBC) disease settings in several preclinical animal models, says the drug’s developer, Enanta Pharmaceuticals ... Read more

April 19, 2017May 12, 2017

Ocera’s Therapy Candidate OCR-002 Prevented Cirrhosis Progression in NAFLD Animal Models

News, Non-alcoholic fatty liver disease

The latest preclinical results of Ocera Therapeutics’ ammonia scavenger OCR-002 showed that it can reduce fibrosis progression in animal models of non-alcoholic fatty liver disease, or NAFLD. The findings, suggesting that OCR-002 ... Read more

April 17, 2017April 19, 2017

Galectin Plans to Present Data from Phase 2 NASH Cirrhosis Trial by Year’s End

Liver cirrhosis, News, Non-alcoholic steatohepatitis

Galectin Therapeutics’s lead drug GR-MD-02 may be a promising therapeutic approach to treat fibrosis in fatty liver disease — or non-alcoholic steatohepatitis (NASH) — based on results from a Phase 1 study. The company is ... Read more

April 4, 2017April 5, 2017

Immune Cells That Produce a Certain Protein Could Be Used to Fight Liver Cancer, Study Reports

Liver cancer, News

A subset of stem cell-derived immune cells, known as iPS-ML, stopped tumor progression and improved survival of mice with liver cancer, a Japanese study showed. The findings suggest the cells ... Read more

April 3, 2017April 5, 2017

TGF-beta Protein Fosters Conversion of Normal Liver Cells to Cancerous, Study Suggests

Liver cancer, News

The transforming growth factor-beta (TGF-beta) protein promotes the conversion of normal liver cells to cancerous cells, a study indicates. It also regulates liver cancer cells’ ability to migrate, the researchers said. Normal ... Read more

March 27, 2017March 30, 2017

Lifestyle Changes in Children Can Improve Fat Levels, Reduce Risk of Disease

News, Non-alcoholic fatty liver disease

A healthy diet and regular physical exercise were found to influence the levels of circulating fatty acids, a type of lipid molecules, and reduce the risk of diabetes and cardiovascular ... Read more

March 21, 2017March 30, 2017

New Lipid Metabolic Pathway Can Help Explain Cancer Drug Resistance

News, Non-alcoholic fatty liver disease

Researchers from Stony Brook University have described a biochemical mechanism that occurs in the liver and is responsible for the conversion of a lipid molecule called ceramide into another called ... Read more