Researchers have identified 27 genetic variants linked to intrahepatic cholestasis of pregnancy (ICP), including those located in 10 newly discovered DNA regions, uncovering key…
Cholestasis
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Cholestasis is a medical term that’s used to describe a slowing or stalling of bile flow out of the liver. Bile is a yellow-greenish fluid produced by the liver that helps to break down certain fatty molecules and proteins into smaller pieces during digestion. It also carries certain waste products from the liver into the intestines to be excreted in feces.
Cholestasis treatment options aim to restore the normal flow of the digestive fluid bile through the bile ducts, a series of tubes that carry the sticky yellow-greenish fluid out of the liver where it's made and to the small intestine.
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Blood levels of xenin-25, a small protein (peptide) produced in the gut, may serve as a biomarker to help diagnose intrahepatic cholestasis of pregnancy,…
People with progressive familial intrahepatic cholestasis (PFIC), along with their families and clinicians, collaborated on a two-year project to develop a knowledge base for…
