Livmarli (maralixibat) and Bylvay (odevixibat) can help relieve itching, or pruritus, and reduce liver damage in children with progressive familial intrahepatic cholestasis (PFIC) or…
A genetic variant unique to East Asians increases the risk of intrahepatic cholestasis of pregnancy (ICP) by more than 16 times, but it likely…
This week I had an appointment with a new doctor to check on my health following my experience with intrahepatic cholestasis of pregnancy (ICP), a…
In real-world use, Kayfanda (odevixibat) — available under the brand name Bylvay in the U.S. — lowered blood bile acid levels and eased…
Enrollment is ongoing in a Phase 3 clinical trial that’s designed to evaluate Mirum Pharmaceuticals’ maralixibat for treatment-resistant itching, or pruritus, associated with rare…
A combination of two new mutations in the TJP2 gene was identified as the cause of a mild form of progressive familial intrahepatic cholestasis type 4 (PFIC4) in…
I love Christmas. What’s not to like about being with friends and family, taking winter walks, and eating too much food? My dad’s always been…
Higher blood levels of omega-3 fatty acids, fatty molecules found in food and shown to have health benefits, significantly associate with a lower risk of…
Cholestasis is a common complication among critically ill people with COVID 19-associated acute respiratory distress syndrome (ARDS), a life-threatening form of respiratory failure, a…
Two cases of progressive familial intrahepatic cholestasis type 3 (PFIC3) with markedly different ages of disease onset due to new mutations in the ABCB4…