The U.S. Food and Drug Administration (FDA) has granted accelerated approval to Hepcludex (bulevirtide-gmod), in development by Gilead…
Articles by Steve Bryson, PhD
People with progressive familial intrahepatic cholestasis (PFIC), along with their families and clinicians, collaborated on a two-year project to…
A large clinical trial evaluating Atea Pharmaceuticals’ fixed-dose oral combination of bemnifosbuvir and ruzasvir in adults with chronic…
Low blood levels of vitamin B6 — found in certain foods and essential for metabolism and immune function in the…
Twice-daily treatment with volixibat, Mirum Pharmaceuticals’ oral investigational therapy for primary sclerosing cholangitis (PSC) significantly outperformed a placebo…
In a rat model of segmental cholestasis, a condition in which bile flow is blocked in certain areas of…
Researchers have developed a new mouse model of progressive familial intrahepatic cholestasis type 3 (PFIC3) that more closely mimics…
Clearing senescent macrophages, a type of damaged immune cell that doesn’t die off as it should, reduced inflammation and reversed…
The U.S. Food and Drug Administration (FDA) has granted fast-track designation to pevifoscorvir sodium, Aligos Therapeutics‘ oral therapy candidate…
A genetic susceptibility to gestational diabetes mellitus (GDM), a common pregnancy complication marked by intolerance to blood sugar due to…