Cholestasis

Blood levels of xenin-25, a small protein (peptide) produced in the gut, may serve as a biomarker to help diagnose intrahepatic cholestasis of pregnancy,…

People with progressive familial intrahepatic cholestasis (PFIC), along with their families and clinicians, collaborated on a two-year project to develop a knowledge base for…

A new prediction tool may help assess the risk of preterm birth (before 37 weeks of gestation) in women affected by intrahepatic cholestasis of…

Rare genetic liver conditions like progressive familial intrahepatic cholestasis (PFIC) and Alagille syndrome pose a substantial financial and quality-of-life burden on families, a study…

In a rat model of segmental cholestasis, a condition in which bile flow is blocked in certain areas of the liver, treatment with pioglitazone…

Researchers have developed a new mouse model of progressive familial intrahepatic cholestasis type 3 (PFIC3) that more closely mimics key features of the disease…

Noninvasive scores originally developed to assess liver scarring may help diagnose pregnant women who have intrahepatic cholestasis of pregnancy (ICP), the most common pregnancy-specific…

April 19 marks World Liver Day, a global effort to raise awareness about liver health and the growing burden of liver disease. This year’s…

A genetic susceptibility to gestational diabetes mellitus (GDM), a common pregnancy complication marked by intolerance to blood sugar due to low levels of the insulin…

April is officially recognized in the U.S. as National Donate Life Month, an opportunity to highlight the extraordinary impact of organ donation, and the…