Cholestasis

Rare genetic liver conditions like progressive familial intrahepatic cholestasis (PFIC) and Alagille syndrome pose a substantial financial and quality-of-life burden on families, a study…

In a rat model of segmental cholestasis, a condition in which bile flow is blocked in certain areas of the liver, treatment with pioglitazone…

Researchers have developed a new mouse model of progressive familial intrahepatic cholestasis type 3 (PFIC3) that more closely mimics key features of the disease…

Noninvasive scores originally developed to assess liver scarring may help diagnose pregnant women who have intrahepatic cholestasis of pregnancy (ICP), the most common pregnancy-specific…

April 19 marks World Liver Day, a global effort to raise awareness about liver health and the growing burden of liver disease. This year’s…

A genetic susceptibility to gestational diabetes mellitus (GDM), a common pregnancy complication marked by intolerance to blood sugar due to low levels of the insulin…

April is officially recognized in the U.S. as National Donate Life Month, an opportunity to highlight the extraordinary impact of organ donation, and the…

Blood levels of certain pro-inflammatory proteins are elevated in people with intrahepatic cholestasis of pregnancy (ICP), and these inflammatory markers may help predict the…

Testing for bilirubin, a liver damage marker, in urine is not reliable for screening or diagnosing cholestasis (slowed flow of the digestive fluid bile)…

Researchers in China have developed and validated a new prediction model that can help distinguish pregnant women with intrahepatic cholestasis of pregnancy (ICP) who…