Liver scarring before treatment for hepatitis C predicts cancer risk
People with hepatitis C who show higher values of liver scarring markers before starting antiviral therapy are significantly more likely to later develop…
Michela Luciano, PhD, Science Writer—
Articles by Michela Luciano, PhD
Newly ID’d LSR gene mutations are likely cause of PFIC in 3 children
Newly identified mutations in the LSR gene were the likely cause of progressive familial intrahepatic cholestasis (PFIC) in three unrelated children — two of whom…
Madrigal wins US patent for Rezdiffra dosing regimen in MASH
The U.S. Patent and Trademark Office (USPTO) is granting a patent for Rezdiffra (resmetirom) — Madrigal Pharmaceuticals’ approved therapy for metabolic dysfunction-associated steatohepatitis (MASH),…
Recurrent ICP linked to condition’s severity in 1st pregnancy
Nearly one in three patients diagnosed with intrahepatic cholestasis of pregnancy (ICP) during a first pregnancy will develop the condition again in a subsequent…
Global Phase 3 trial of Atea’s combo therapy doses 1st hep C patient
The first participant has been dosed in a Phase 3 clinical trial testing Atea Pharmaceuticals’ combination therapy of bemnifosbuvir and ruzasvir in people with chronic…
Elevated skull pressure leads to vision loss in Alagille: Case study
A young woman with Alagille syndrome (AGLS) developed profound vision loss due to increased pressure inside the skull following multiple brain bleeds, according to…
New JAG1 mutation seen as likely cause of Alagille case
Researchers have identified a new mutation in the JAG1 gene as the likely cause of Alagille syndrome in an 18-year-old man who also had persistent…