The experimental oral therapy linerixibat from GlaxoSmithKline (GSK) offers rapid and sustained relief from severe itch in adults with primary biliary cholangitis (PBC),…
News
CHOLESTASIS
NewsTwo new USP53 gene mutations cause mild PFIC in Russian boy
Two new mutations in the USP53 gene were identified as the cause of a milder form of progressive familial intrahepatic cholestasis (PFIC), which resembled…
FATTY LIVER DISEASE
NewsToo much sorbitol may raise fatty liver disease risk, study finds
Excessive intake of sorbitol, a type of sugar naturally found in many fruits and used as a sugar substitute, may increase the risk of metabolic…
CHOLANGITIS
NewsNebokitug reduces immune cell activity that drives PSC: Data
Nebokitug, an experimental infusion therapy being developed by Chemomab Therapeutics for primary sclerosing cholangitis (PSC), reduces the inflammatory…
CHOLESTASIS
NewsNew biomarkers may help detect pregnancy-linked liver complication
Levels of the metabolite palmitic acid and the protein ACSL1 in the bloodstream can accurately detect the presence and severity of intrahepatic cholestasis of…
FATTY LIVER DISEASE
NewsBelapectin may help reduce liver scarring in those with severe MASH
Galectin Therapeutics‘ experimental medication belapectin may help reduce liver scarring, or fibrosis, and lower the risk of blood vessel complications in people with metabolic-associated…
BILIARY ATRESIA
NewsStem cell therapy may boost liver health in infants with biliary atresia
Therapy using stem cells derived from donor umbilical cords may help improve outcomes in infants with biliary atresia who have undergone standard Kasai surgery,…
New modeling data predict that bemnifosbuvir and ruzasvir, an experimental combination treatment being developed by Atea Pharmaceuticals for chronic hepatitis C, may…
CHOLANGITIS
NewsNew trial testing probiotic for reducing liver inflammation in PSC
Liscure Biosciences has launched a Phase 2 clinical trial to test whether its experimental probiotic LB-P8 can improve gut health and reduce liver inflammation…
CHOLESTASIS
NewsMelatonin may protect the liver from cholestasis-related injury
Treatment with melatonin, a naturally occurring hormone best known for regulating sleep, may help reduce liver injury caused by cholestasis, according to a study…
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