The first participant has been dosed in a large clinical trial testing TGM-312, a novel gene-silencing therapy designed to slow the progression of metabolic dysfunction-associated…
News
ALAGILLE SYNDROME
NewsBlood bile acids predict liver outcomes in Alagille syndrome children: Study
Children with Alagille syndrome who have lower blood levels of bile acids, the main component of the digestive fluid bile, have better long-term liver…
In preclinical studies, AT-587, Atea Pharmaceuticals’ lead oral candidate for treating hepatitis E, showed potent antiviral activity against multiple strains of the hepatitis…
Use of the experimental immune-modulating therapy CNP-104 in adults with primary biliary cholangitis (PBC) participating in a U.S. clinical trial led to greater reductions in markers…
Among children and adolescents with progressive familial intrahepatic cholestasis (PFIC), severe itch significantly affects sleep, overall perceptions of health, and the family’s quality of…
FATTY LIVER DISEASE
NewsParental obesity triples risk of early liver disease in children, new study finds
People whose biological parents were overweight or obese at the time of their conception face a greater risk of early liver disease, according to a…
BILIARY ATRESIA
NewsNew animated video aims to support children living with biliary atresia
The American Liver Foundation (ALF) has brought its “Bili the Brave” children’s book to life with a new animated video that aims to support…
One-time treatment with VRON-0200 reduced hepatitis B virus (HBV) levels in the blood of most people with chronic hepatitis B — early trial findings…
People with primary biliary cholangitis (PBC) who don’t start treatment after being diagnosed with the liver disease end up hospitalized more often and for…
Progressive familial intrahepatic cholestasis type 3 (PFIC3) can cause abnormalities in copper metabolism that mimic another condition, Wilson’s disease, and early distinction is key…
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