Off-label treatment with Mirum Pharmaceuticals’ maralixibat led to clinically meaningful reductions in severe itching, or pruritus, in five children…
Steve Bryson, PhD
Steve holds a PhD in biochemistry from the Faculty of Medicine at the University of Toronto, Canada. As a medical scientist for 18 years, he worked in both academia and industry, where his research focused on the discovery of new vaccines and medicines to treat inflammatory disorders and infectious diseases. Steve is a published author in multiple peer-reviewed scientific journals and a patented inventor.
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Articles by Steve Bryson, PhD
CHOLANGITIS
NewsFDA rejects full approval of Ocaliva as second-line PBC treatment
The U.S. Food and Drug Administration (FDA) has turned down a request by Intercept Pharmaceuticals for the full approval of…
CHOLESTASIS
NewsIVF linked to higher rates of cholestasis pregnancy complication
Women who conceive with the help of in vitro fertilization (IVF) — a commonly used assisted reproductive technology — are…
FATTY LIVER DISEASE
NewsLanifibranor may be reason for liver gains seen in Phase 3 MASH trial
Signs of improved liver health are evident in biomarker and liver scarring assessments of people with metabolic-associated steatohepatitis or MASH…
FATTY LIVER DISEASE
NewsResearchers identify pathway behind MASLD-linked mutation
A study showed that a genetic mutation associated with metabolic dysfunction-associated steatotic liver disease (MASLD), a form of fatty…
Two weeks of oral methylprednisolone twice a day as an add-therapy significantly lowered signs of liver damage and inflammation among…
BILIARY ATRESIA
NewsBlood test augurs liver survival after Kasai procedure in biliary atresia
A blood-based biomarker of body-wide inflammation called a low systemic immune-inflammation index (SII) before a standard Kasai surgical procedure…
CHOLANGITIS
NewsPBC treatment setanaxib eases signs of liver damage: Trial data
Six months of Calliditas Therapeutics‘ investigational therapy setanaxib safely and significantly reduced signs of liver damage in people with…
FATTY LIVER DISEASE
NewsDosing begins in Phase 2 trial of DD01 in treating fatty liver disease
Dosing has begun in a Phase 2 clinical trial evaluating the safety and efficacy of DD01 in people with one of…
In its efforts to connect diagnosed but untreated hepatitis B or C patients with physicians, the Center for…