AusperBio raised $50 million to advance the development of chronic hepatitis B treatment AHB-137. The company said the funding will help it launch Phase…
News
CHOLANGITIS
NewsFDA to review linerixibat for PBC-related itching
The U.S. Food and Drug Administration (FDA) has accepted for review GSK’s application seeking the approval of its oral treatment linerixibat for intense itching, or…
A novel mutation in the ATP8B1 gene was the likely cause of progressive familial intrahepatic cholestasis (PFIC) type 1 in two siblings in India…
FATTY LIVER DISEASE
NewsFatty liver disease MASLD to affect 16% of teens, young adults by 2050
The total number of adolescents and young adults with metabolic dysfunction-associated steatotic liver disease (MASLD), a form of fatty liver disease, has been steadily…
BILIARY ATRESIA
NewsEarly Kasai surgery linked to better outcomes, lower care costs in US
The cumulative healthcare costs for infants with biliary atresia can increase substantially if they undergo their initial treatment, the Kasai surgery, after 2 months…
People with hepatitis C in the U.S. who are insured through state Medicaid programs that require them to be sober to access treatment are…
CHOLANGITIS
News30% rise due in primary sclerosing cholangitis prevalence by 2040
The global prevalence of primary sclerosing cholangitis (PSC), or the total number of existing cases, is expected to increase substantially over the next several…
CHOLESTASIS
NewsACER3 enzyme may be therapeutic target in cholestasis: Lab study
ACER3, an enzyme involved in the metabolism of fat-like signaling molecules known as ceramides, plays a detrimental role in cholestasis-related liver damage — and,…
ALAGILLE SYNDROME
NewsElevated skull pressure leads to vision loss in Alagille: Case study
A young woman with Alagille syndrome (AGLS) developed profound vision loss due to increased pressure inside the skull following multiple brain bleeds, according to…
The investigational treatment imdusiran used as part of combination therapy regimens has led to a functional cure for eight people with chronic hepatitis…
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