The first participant has been enrolled in ECLIPSE 3, a Phase 2b clinical trial testing Vir Biotechnology’s combination treatment of tobevibart and elebsiran against…
News
CHOLANGITIS
NewsAdding Vitamin D boosts PBC treatment in clinical trial
Adding vitamin D to ursodeoxycholic acid (UDCA) treatment is superior to UDCA alone at reducing symptoms, liver damage markers, and liver scarring in previously untreated…
CHOLESTASIS
NewsStudy links low vitamin D to severe liver damage in cholestasis
Low levels of vitamin D by-products, or metabolites, in the blood are indicative of more severe liver damage in cholestasis, according to a small…
FATTY LIVER DISEASE
NewsStudy testing fatty liver disease MASH therapy almost fully enrolled
Enrollment is nearly complete in a Phase 2b clinical trial that’s testing Corcept Therapeutics‘ experimental oral therapy miricorilant in people with metabolic-associated steatohepatitis (MASH),…
ALAGILLE SYNDROME
NewsNew mutation props up woman’s Alagille syndrome diagnosis
An unreported mutation in the JAG1 gene was identified as the likely cause of Alagille syndrome in a 28-year-old woman, a case report from…
About 74,000 babies are born each year with the virus that causes hepatitis C, and more than 23,000 of them may still have the…
CHOLANGITIS
NewsLarge study finds risks of liver cancer low for certain PSC patients
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is relatively rare among people with primary sclerosing cholangitis (PSC) who do not have…
CHOLESTASIS
NewsGenetic testing helps identify cause of neonatal cholestasis
Genetic testing can help doctors find the cause of neonatal cholestasis more quickly, so children can receive more targeted treatment sooner, according to a…
FATTY LIVER DISEASE
NewsHoth, VA partner on head-to-head study in fatty liver disease mice
Hoth Therapeutics will support a U.S. Department of Veterans Affairs (VA) study testing treatment with glial cell-derived neurotrophic factor (GDNF) against semaglutide in a…
BILIARY ATRESIA
NewsStudy reveals disease mechanisms that may drive biliary atresia
A new preclinical study has found that a combination of viral and bacterial insults may be a key disease mechanism underlying biliary atresia. Specifically,…
Recent Posts
- With Alagille syndrome, summer fun comes with a summer caution
- Gene therapy shows early promise for fatal childhood liver disease
- Large VA study reveals hidden liver damage in US military veterans
- Uncle’s living donation saves 1-year-old girl with liver failure
- With FDA support, developer planning late-stage trial of belapectin for MASH