Long-term treatment with Rezdiffra (resmetirom) reduces liver scarring for most people with compensated cirrhosis, or irreversible scarring in a still-functioning liver, due to metabolic…
News
ALAGILLE SYNDROME
News6 JAG1, NOTCH2 gene mutations ID’d as likely cause of Alagille
Researchers in China have identified six new mutations in the JAG1 and NOTCH2 genes as likely causes of Alagille syndrome. In…
A program using a telemedicine approach to treat hepatitis C in people with opioid use disorder that resulted in the cure of more than…
Gilead Sciences’ oral therapy seladelpar has been conditionally approved by the European Commission as a second-line therapy for adults with primary biliary…
CHOLESTASIS
NewsCombo of variants in ABCB4 gene could lead to ICP, study finds
A specific variant in the ABCB4 gene does not cause intrahepatic cholestasis of pregnancy (ICP) on its own, but it may increase the disease’s…
FATTY LIVER DISEASE
NewsAlgorithm spots people with MASLD, MASH using health records
Researchers have developed an algorithm to identify people with metabolic dysfunction-associated steatotic liver disease (MASLD), a type of fatty liver disease, based on information…
BILIARY ATRESIA
NewsPatient identification guidelines may help diagnose biliary atresia earlier
A team of experts in the U.S. and Canada have developed patient identification guidelines to help pediatric primary care providers, or PCPs, in making an…
A single dose of Precision BioSciences’ investigational gene-editing therapy PBGENE-HBV was well tolerated and showed early signs of antiviral activity among three adults with…
CHOLANGITIS
News2nd liver transplant linked to good outcomes in PSC
A second liver transplant results in transplant and patient outcomes in people with primary sclerosing cholangitis (PSC) that are comparable or better than those…
CHOLESTASIS
NewsAI models may aid intrahepatic cholestasis of pregnancy prediction
New artificial intelligence (AI) models based on 11 possible risk factors of intrahepatic cholestasis of pregnancy (ICP) can accurately distinguish between healthy pregnant women,…
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