Primary sclerosing cholangitis (PSC) patients with inflammatory bowel disease (IBD) face a higher risk of liver-related complications and the need for a liver transplant…
News
Volixibat, Mirum Pharmaceuticals’ experimental oral treatment, may help reduce circulating bile acids and ease itch in pregnant women with intrahepatic cholestasis of pregnancy…
FATTY LIVER DISEASE
NewsIn proof-of-concept trial, daily pill lowers blood, liver fat levels in MASLD
Daily treatment with Orsobio’s oral candidate TLC-2716 reduces fat levels in both the blood and liver in overweight adults with high blood fat levels…
BILIARY ATRESIA
NewsRare biliary atresia variant linked to better clinical outcomes: China study
Infants with cystic biliary atresia (CBA) tend to undergo standard Kasai surgery earlier than those with other forms of biliary atresia, and generally have…
A new test that uses a tiny drop of blood collected from a finger prick and returns results in about an hour can detect…
A noninvasive liver scan used alongside a standard blood test may accurately predict the severity of liver scarring, or fibrosis, in people with primary…
Health Canada has approved Mirum Pharmaceuticals’ oral therapy Livmarli (maralixibat) for cholestatic pruritus — that is, itching due to impaired bile flow —…
FATTY LIVER DISEASE
NewsCoalition to push for earlier diagnosis of fatty liver disease MASLD
Mashnet, a network of health organizations in the U.S. and Europe, formed a coalition to broaden access to noninvasive diagnostic tools that can detect metabolic…
ALAGILLE SYNDROME
NewsCanada approves Livmarli oral tablets for Alagille itching
An oral tablet formulation of Livmarli (maralixibat) is now approved in Canada to treat pruritus (itching) caused by Alagille syndrome. An oral solution…
Dosing has begun in a Phase 1/2 clinical trial testing CRMA-1001, Nchroma Bio’s experimental epigenetic therapy being studied as a potential functional cure for…
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