News

In a rat model of segmental cholestasis, a condition in which bile flow is blocked in certain areas of the liver, treatment with pioglitazone…

A once-monthly investigational therapy for metabolic dysfunction-associated steatohepatitis (MASH), called efimosfermin, has earned two new regulatory designations — one in the U.S. and the other…

Due to limited access to genetic testing, a young girl with Alagille syndrome in Indonesia was misdiagnosed in infancy with biliary atresia —…

The U.S. Food and Drug Administration (FDA) has accepted and placed under priority review an application seeking approval of bepirovirsen, GlaxoSmithKline (GSK)’s investigational therapy,…

Adults with primary biliary cholangitis (PBC) who have less elevated blood levels of the liver enzyme alkaline phosphatase (ALP), a marker of liver damage, at…

Researchers have developed a new mouse model of progressive familial intrahepatic cholestasis type 3 (PFIC3) that more closely mimics key features of the disease…

Clearing senescent macrophages, a type of damaged immune cell that doesn’t die off as it should, reduced inflammation and reversed signs of liver fat buildup…

Investing in hepatitis C testing and treatment may actually lower healthcare costs over time, according to a new study from Washington state. By catching…

Scheduled MRI scans one to three years after a liver transplant may detect signs of returning primary sclerosing cholangitis (PSC) earlier than standard blood-based liver…

Noninvasive scores originally developed to assess liver scarring may help diagnose pregnant women who have intrahepatic cholestasis of pregnancy (ICP), the most common pregnancy-specific…