Testing for bilirubin, a liver damage marker, in urine is not reliable for screening or diagnosing cholestasis (slowed flow of the digestive fluid bile)…
News
FATTY LIVER DISEASE
NewsTrial of WVE-007 for obesity aims to inform decisions about drug for MASH
An upcoming portion of an ongoing clinical trial that will test Wave Life Sciences’ WVE-007 in adults with obesity and related health problems will…
BILIARY ATRESIA
NewsMost babies with biliary atresia test positive for rotavirus antibodies
Most infants with the rare liver disease biliary atresia (BA) show signs of a previous rotavirus infection, suggesting the common childhood virus may play…
Mirum Pharmaceuticals is making progress with a quartet of late-stage clinical trials designed to test brelovitug, the company’s experimental therapy for chronic hepatitis…
CHOLANGITIS
NewsStudy indicates which PBC patients may see liver function recovery
Primary biliary cholangitis (PBC) patients who have irreversible liver scarring that affects the organ’s function are more likely to experience liver function recovery if…
Researchers in China have developed and validated a new prediction model that can help distinguish pregnant women with intrahepatic cholestasis of pregnancy (ICP) who…
FATTY LIVER DISEASE
NewsHK2 protein identified as potential treatment target for MASH: Study
Two proteins called S100A11 and HK2 contribute to the abnormal buildup of fat in the liver that characterizes steatotic liver disease (SLD), according to…
ALAGILLE SYNDROME
NewsFirst reported case links Alagille syndrome with biliary atresia
A baby girl with Alagille syndrome and related liver problems that were not responding to standard medication was also diagnosed with a rare liver…
Lynavoy (linerixibat) is now approved in the U.S. as an oral treatment for cholestatic pruritus, or intense itch due to problems in how the digestive…
Backed by millions in U.S. funding, scientists from Johns Hopkins Medicine in Baltimore will be leading a new international consortium working to find a cure…
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