Blood levels of xenin-25, a small protein (peptide) produced in the gut, may serve as a biomarker to help diagnose intrahepatic cholestasis of pregnancy,…
News
FATTY LIVER DISEASE
NewsWegovy MASH benefits seen across patient groups in trial analyses
Treatment with Wegovy (semaglutide) showed a consistent safety and efficacy profile across a range of patient subgroups with metabolic dysfunction-associated steatohepatitis (MASH), a serious…
ALAGILLE SYNDROME
NewsLivmarli helps clear fatty skin growths in Alagille kids, study finds
Treatment with Livmarli (maralixibat) can reduce cholesterol levels and help clear fatty skin growths called xanthomas in children with Alagille syndrome, according to…
PBGENE-HBV, Precision Biosciences’ experimental gene-editing therapy for chronic hepatitis B, showed early evidence of eliminating and inactivating hepatitis B viral DNA as designed,…
CHOLANGITIS
NewsOral ABI-6250 may move into Phase 2 clinical testing for PBC and PSC
Assembly Biosciences plans to develop its investigational oral treatment, ABI-6250, for people with primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC). The…
The U.S. Food and Drug Administration (FDA) has granted accelerated approval to Hepcludex (bulevirtide-gmod), in development by Gilead Sciences, for treating adults with…
CHOLESTASIS
NewsProject gives PFIC families a voice in liver treatment research
People with progressive familial intrahepatic cholestasis (PFIC), along with their families and clinicians, collaborated on a two-year project to develop a knowledge base for…
BILIARY ATRESIA
NewsBiliary atresia, Alagille linked to oral problems in children, young adults
Children and young adults with biliary atresia or Alagille syndrome more frequently experience oral problems and poor oral hygiene than their healthy peers,…
A large clinical trial evaluating Atea Pharmaceuticals’ fixed-dose oral combination of bemnifosbuvir and ruzasvir in adults with chronic hepatitis C remains on track,…
CHOLANGITIS
NewsItching drives healthcare costs higher for PBC patients, study finds
People with primary biliary cholangitis (PBC) who experience itching (pruritus) use more healthcare resources and have significantly higher medical costs than those without this…
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