As many as 1 in 4 U.S. military veterans with the liver disease primary biliary cholangitis (PBC) may have irreversible liver scarring, or cirrhosis,…
Cholangitis
Various factors, including male sex and younger age, were associated with an increased risk of primary sclerosing cholangitis (PSC) recurrence after liver transplant, according…
A team of scientists has identified two key immune proteins — CD58 and IL7R — as therapeutic targets in primary biliary cholangitis (PBC), with…
CHOLANGITIS
NewsLivdelzi lowers liver damage marker across PBC trials, data show
Gilead Sciences‘ Livdelzi (seladelpar) effectively reduces blood levels of alkaline phosphatase (ALP), a key marker of liver damage, in most people with primary…
CHOLANGITIS
NewsOral ABI-6250 may move into Phase 2 clinical testing for PBC and PSC
Assembly Biosciences plans to develop its investigational oral treatment, ABI-6250, for people with primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC). The…
CHOLANGITIS
NewsItching drives healthcare costs higher for PBC patients, study finds
People with primary biliary cholangitis (PBC) who experience itching (pruritus) use more healthcare resources and have significantly higher medical costs than those without this…
Low blood levels of vitamin B6 — found in certain foods and essential for metabolism and immune function in the body — can increase the…
Twice-daily treatment with volixibat, Mirum Pharmaceuticals’ oral investigational therapy for primary sclerosing cholangitis (PSC) significantly outperformed a placebo in reducing moderate to severe…
CHOLANGITIS
NewsStarting disease marker levels may shape Iqirvo response in PBC
Adults with primary biliary cholangitis (PBC) who have less elevated blood levels of the liver enzyme alkaline phosphatase (ALP), a marker of liver damage, at…
CHOLANGITIS
NewsMRI scans catch early signs of PSC recurrence after liver transplant
Scheduled MRI scans one to three years after a liver transplant may detect signs of returning primary sclerosing cholangitis (PSC) earlier than standard blood-based liver…
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