Two plant-based compounds — ferulic acid and wogonin — may help protect the liver in cholestasis by influencing the growth of certain gut bacteria,…
Cholestasis
Women who develop severe intrahepatic cholestasis of pregnancy (ICP) at a later time in pregnancy have a higher risk of stillbirth, a study shows.
CHOLESTASIS
NewsHeart complications common in children with PFIC, study finds
About half of children with progressive familial intrahepatic cholestasis (PFIC) were found to have cirrhotic cardiomyopathy (CCM), a form of heart disease, in a…
CHOLESTASIS
NewsCommon virus may play a role in ICP development, study finds
Infection with human cytomegalovirus (HCMV), a common and usually harmless virus, may play a role in the development of intrahepatic cholestasis of pregnancy (ICP),…
CHOLESTASIS
NewsTwo new USP53 gene mutations cause mild PFIC in Russian boy
Two new mutations in the USP53 gene were identified as the cause of a milder form of progressive familial intrahepatic cholestasis (PFIC), which resembled…
CHOLESTASIS
NewsNew biomarkers may help detect pregnancy-linked liver complication
Levels of the metabolite palmitic acid and the protein ACSL1 in the bloodstream can accurately detect the presence and severity of intrahepatic cholestasis of…
CHOLESTASIS
NewsMelatonin may protect the liver from cholestasis-related injury
Treatment with melatonin, a naturally occurring hormone best known for regulating sleep, may help reduce liver injury caused by cholestasis, according to a study…
CHOLESTASIS
NewsNovel gene mutation is likely cause of newborn’s rare liver disease
A novel mutation in the NR1H4Â gene was the likely cause of progressive familial intrahepatic cholestasis (PFIC) type 5 in a baby girl in Tunisia,…
CHOLESTASIS
News2 simple nutrients may be effective new screening tool for ICP
A new study has identified two dietary nutrients, choline and dimethylglycine, as effective potential biomarkers for diagnosing and monitoring intrahepatic cholestasis of pregnancy (ICP).
CHOLESTASIS
NewsItching was main sign of teen’s liver disease: Case report
Itching was the main symptom leading to the diagnosis of progressive familial intrahepatic cholestasis (PFIC) type 3 in a teenage boy in Portugal, a…
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