Know your risks – and options – this National Liver Awareness Month
October is National Liver Awareness Month and Liver Cancer Awareness Month, and advocacy organizations across the U.S., including the American Liver Foundation (ALF), are…
Cholestasis
PFIC Awareness Day means… spotlighting the rare liver disease
Supporters are gearing up for the 7th Annual PFIC Awareness Day on Oct. 5, with advocates behind the yearly event focused on improving public awareness,…
Newly ID’d LSR gene mutations are likely cause of PFIC in 3 children
Newly identified mutations in the LSR gene were the likely cause of progressive familial intrahepatic cholestasis (PFIC) in three unrelated children — two of whom…
Hormone-like therapy NF-1 shows promise in ICP mouse study
Nesfatin-1 (NF-1), a hormone-like molecule that may ease cellular stress, reduced injury to the placenta in a mouse model of intrahepatic cholestasis of pregnancy…
LSR gene mutations may cause new type of rare liver disease PFIC
Mutations in the LSR gene, including one previously unreported, were the likely cause of progressive familial intrahepatic cholestasis (PFIC) in two young children in Turkey,…
New medications show promise for children with rare liver disease
While different types of progressive familial intrahepatic cholestasis (PFIC) vary in their genetic cause and clinical profile, new medications like Bylvay (odevixibat) and Livmarli…
Targeting mitochondrial problems eases cholestasis in mouse model
Problems in mitochondria, the cell’s powerhouses, may contribute to liver damage associated with cholestasis and represent a potential therapeutic target, a study showed. Deteriorating…
Maternal liver damage markers can predict twin pregnancy outcomes
High maternal levels of liver damage markers in the blood can predict poor fetal outcomes in twin pregnancies affected by intrahepatic cholestasis of pregnancy…
AI tool uses liver tests to ID genetic forms of cholestasis in infants
A new artificial intelligence (AI) algorithm can help identify babies with genetic forms of cholestasis, including progressive familial intrahepatic cholestasis (PFIC), using data from…
Study links low vitamin D to severe liver damage in cholestasis
Low levels of vitamin D by-products, or metabolites, in the blood are indicative of more severe liver damage in cholestasis, according to a small…
Recent Posts
- Drug combo shrinks liver fat in rats and zebrafish: Study
- Know your risks – and options – this National Liver Awareness Month
- Enrollment complete in 2 Phase 2 trials testing hepatitis B treatment
- PBC worst for life quality among autoimmune liver diseases: Study
- Changes big and small can benefit those of us with MASH