Mirum Pharmaceuticals is making progress with a quartet of late-stage clinical trials designed to test brelovitug, the company’s experimental therapy for chronic hepatitis…
News
CHOLANGITIS
NewsStudy indicates which PBC patients may see liver function recovery
Primary biliary cholangitis (PBC) patients who have irreversible liver scarring that affects the organ’s function are more likely to experience liver function recovery if…
Researchers in China have developed and validated a new prediction model that can help distinguish pregnant women with intrahepatic cholestasis of pregnancy (ICP) who…
FATTY LIVER DISEASE
NewsHK2 protein identified as potential treatment target for MASH: Study
Two proteins called S100A11 and HK2 contribute to the abnormal buildup of fat in the liver that characterizes steatotic liver disease (SLD), according to…
ALAGILLE SYNDROME
NewsFirst reported case links Alagille syndrome with biliary atresia
A baby girl with Alagille syndrome and related liver problems that were not responding to standard medication was also diagnosed with a rare liver…
Lynavoy (linerixibat) is now approved in the U.S. as an oral treatment for cholestatic pruritus, or intense itch due to problems in how the digestive…
Backed by millions in U.S. funding, scientists from Johns Hopkins Medicine in Baltimore will be leading a new international consortium working to find a cure…
CHOLANGITIS
NewsMRI biomarker may predict PSC liver complications: Study
A noninvasive MRI-based approach may help assess disease severity and predict the likelihood of serious complications in people with primary sclerosing cholangitis (PSC), a…
A global clinical trial testing Mirum Pharmaceuticals’ oral therapy maralixibat in people with itching, or pruritus, due to rare cholestatic conditions has finished…
FATTY LIVER DISEASE
NewsTrial of combo therapy for MASH-related cirrhosis to start this year
Sagimet Biosciences said it expects a clinical trial testing a combination therapy in people with cirrhosis, or irreversible liver scarring, due to metabolic dysfunction-associated steatohepatitis…
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