Long-term ketogenic diet may cause fatty liver disease, per mouse study
A long-term ketogenic diet, which favors fats over carbs, may promote weight loss, but it can also cause fatty liver disease and blood sugar…
News
Potential biliary atresia treatment AX-0810 to enter clinical testing
AX-0810, an experimental medication Proqr Therapeutics is developing for biliary atresia and another liver disease called primary sclerosing cholangitis (PSC), is about to…
Autoimmune hepatitis therapy hits FDA roadblock, future uncertain
Kezar Life Sciences has hit a roadblock in plans to develop zetomipzomib, its experimental treatment for autoimmune hepatitis (AIH). The company has…
Seladelpar approved in Canada as Lyvdelzi to treat adults with PBC
Health Canada has conditionally approved Gilead Sciences’ seladelpar — to be marketed in the country under the brand name Lyvdelzi — as a second-line…
Itching was main sign of teen’s liver disease: Case report
Itching was the main symptom leading to the diagnosis of progressive familial intrahepatic cholestasis (PFIC) type 3 in a teenage boy in Portugal, a…
New Helix dataset aims to accelerate liver disease research
A new dataset from genomics company Helix aims to accelerate research into metabolic dysfunction-associated steatohepatitis (MASH), a severe form of fatty liver disease.
Livmarli eases Alagille teen’s itch following liver transplant issues
Treatment with Livmarli (maralixibat) quickly and safely reduced severe itching in a 16-year-old boy with Alagille syndrome after his transplanted liver started to malfunction,…
US enrollment starts for hepatitis B gene therapy clinical trial
A Phase 1 clinical trial testing PBGENE-HBV, a gene-editing therapy for chronic hepatitis B, is now recruiting patients at Massachusetts General Hospital in…
Women with PBC may be at high risk of disease flares after childbirth
Women with primary biliary cholangitis (PBC) may be at increased risk of having disease flares in the months following childbirth, according to a small…
Agrimonolide shows benefits in cholestasis mouse model
Agrimonolide, a molecule found in a traditional Chinese herb, eased liver damage, scarring, and inflammation in a mouse model of cholestasis, a study showed.
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