Heart complications common in children with PFIC, study finds
About half of children with progressive familial intrahepatic cholestasis (PFIC) were found to have cirrhotic cardiomyopathy (CCM), a form of heart disease, in a…
Cholestasis
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Cholestasis overview: What you need to know
Cholestasis is a medical term that’s used to describe a slowing or stalling of bile flow out of the liver. Bile is a yellow-greenish fluid produced by the liver that helps to break down certain fatty molecules and proteins into smaller pieces during digestion. It also carries certain waste products from the liver into the intestines to be excreted in feces.
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Cholestasis treatment and management options
Cholestasis treatment options aim to restore the normal flow of the digestive fluid bile through the bile ducts, a series of tubes that carry the sticky yellow-greenish fluid out of the liver where it's made and to the small intestine.
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Common virus may play a role in ICP development, study finds
Infection with human cytomegalovirus (HCMV), a common and usually harmless virus, may play a role in the development of intrahepatic cholestasis of pregnancy (ICP),…
Two new USP53 gene mutations cause mild PFIC in Russian boy
Two new mutations in the USP53 gene were identified as the cause of a milder form of progressive familial intrahepatic cholestasis (PFIC), which resembled…
