Aramchol shows promise as PSC treatment, mouse study finds
Aramchol, a small molecule in the Galmed Pharmaceuticals pipeline, prevented and reversed inflammation and scarring (fibrosis) of the bile ducts in mouse models of…
Margarida Maia, PhD, Science Writer—
Articles by Margarida Maia
PBC worst for life quality among autoimmune liver diseases: Study
Adults with autoimmune liver disease experience lower quality of life, especially those with primary biliary cholangitis (PBC), who report more fatigue, sleepiness, and pain…
Bylvay now approved in Canada to treat adults, children with Alagille
Bylvay (odevixibat), an oral medication used to treat cholestatic pruritus — severe itching that results from a buildup of bile acids used in digestion —…
Adding Vitamin D boosts PBC treatment in clinical trial
Adding vitamin D to ursodeoxycholic acid (UDCA) treatment is superior to UDCA alone at reducing symptoms, liver damage markers, and liver scarring in previously untreated…
Thousands of babies born each year with hepatitis C infection
About 74,000 babies are born each year with the virus that causes hepatitis C, and more than 23,000 of them may still have the…
Genetic testing helps identify cause of neonatal cholestasis
Genetic testing can help doctors find the cause of neonatal cholestasis more quickly, so children can receive more targeted treatment sooner, according to a…
Bylvay eases itching in episodic PFIC1, boosting daily life: Study
Bylvay (odevixibat) eased pruritus — itching — during episodes of progressive familial intrahepatic cholestasis (PFIC) type 1 caused by mutations in both copies of…
BARE holds Live and Let Live(r) fundraising campaign
Throughout July, the nonprofit Biliary Atresia Research & Education (BARE) is holding its Live and Let Live(r) fundraising campaign to raise money and awareness…
Antibody brings proteins together to tame autoimmune hepatitis
BiTS, an antibody co-developed by researchers at New York University (NYU) to tame overactive immune T-cells, reduced inflammation and liver damage in a study that…
Imbalance of certain fatty molecules may signal disease severity in PSC
An imbalance in the blood between long-chain and very long-chain ceramides — fatty molecules that help fine-tune the body’s inflammatory response — may help indicate…