People with primary sclerosing cholangitis (PSC) have a six times higher risk of cancer affecting the large intestine or rectum, and that risk remained…
News
A new artificial intelligence (AI) algorithm can help identify babies with genetic forms of cholestasis, including progressive familial intrahepatic cholestasis (PFIC), using data from…
FATTY LIVER DISEASE
NewsFatty liver disease linked to projected rise in liver cancer
The proportion of cases of hepatocellular carcinoma (HCC) attributable to fatty liver disease is set to rise in the next 25 years, with obesity…
BILIARY ATRESIA
NewsStudy finds a new player behind liver scarring in biliary atresia
A new study has uncovered a key mechanism behind the liver scarring seen in biliary atresia (BA), a rare liver disease in infants. Two…
The first participant has been enrolled in ECLIPSE 3, a Phase 2b clinical trial testing Vir Biotechnology’s combination treatment of tobevibart and elebsiran against…
CHOLANGITIS
NewsAdding Vitamin D boosts PBC treatment in clinical trial
Adding vitamin D to ursodeoxycholic acid (UDCA) treatment is superior to UDCA alone at reducing symptoms, liver damage markers, and liver scarring in previously untreated…
CHOLESTASIS
NewsStudy links low vitamin D to severe liver damage in cholestasis
Low levels of vitamin D by-products, or metabolites, in the blood are indicative of more severe liver damage in cholestasis, according to a small…
FATTY LIVER DISEASE
NewsStudy testing fatty liver disease MASH therapy almost fully enrolled
Enrollment is nearly complete in a Phase 2b clinical trial that’s testing Corcept Therapeutics‘ experimental oral therapy miricorilant in people with metabolic-associated steatohepatitis (MASH),…
ALAGILLE SYNDROME
NewsNew mutation props up woman’s Alagille syndrome diagnosis
An unreported mutation in the JAG1 gene was identified as the likely cause of Alagille syndrome in a 28-year-old woman, a case report from…
About 74,000 babies are born each year with the virus that causes hepatitis C, and more than 23,000 of them may still have the…
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