AX-0810, an experimental treatment for biliary atresia and primary sclerosing cholangitis (PSC), has so far been well tolerated in early clinical testing. Initial…
News
HEPATITIS
NewsClinical trial results support bepirovirsen for hepatitis B
Bepirovirsen added to standard-of-care medications led to higher functional cure rates for people with chronic hepatitis B than standard treatments alone, according to top-line…
Vitamin D was shown to ease the effects of liver inflammation and damage in primary biliary cholangitis (PBC), a chronic form of cholangitis,…
Low vitamin D levels in the first trimester of pregnancy are significantly associated with an increased risk of developing intrahepatic cholestasis of pregnancy (ICP),…
FATTY LIVER DISEASE
NewsMadrigal acquires ervogastat to help boost MASH treatment options
Madrigal Pharmaceuticals, the maker of Rezdiffra (resmetiron), has acquired three new experimental treatments for metabolic dysfunction-associated steatohepatitis (MASH), a severe form of fatty…
ALAGILLE SYNDROME
NewsAlagille syndrome linked to glaucoma risk in study of 2 brothers
Two adult brothers with impaired vision due to glaucoma, a serious eye condition that may lead to irreversible vision loss, were found to have…
Health Canada has expanded its approval of Abbvie’s oral therapy Maviret (glecaprevir/pibrentasvir), making it the first eight-week, pan-genotypic treatment available for both acute and…
CHOLANGITIS
NewsNew study finds higher cancer risk in PSC with advanced dysplasia
Liver transplant may help prevent bile duct cancer in people with primary sclerosing cholangitis (PSC) who have advanced bile duct dysplasia, a serious…
CHOLESTASIS
NewsPlant compounds offer new clues about gut bacteria and cholestasis
Two plant-based compounds — ferulic acid and wogonin — may help protect the liver in cholestasis by influencing the growth of certain gut bacteria,…
FATTY LIVER DISEASE
NewsPemvidutide advances toward Phase 3 after strong MASH fibrosis results
About one year of treatment with Altimmune’s experimental therapy pemvidutide led to reductions in noninvasive markers of liver scarring (fibrosis) in people with metabolic…
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